HAMP, hepcidin antimicrobial peptide, 57817

N. diseases: 377; N. variants: 15
Disease: Cooley's anemia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002875
Disease: Cooley's anemia
Cooley's anemia 		0.370 Biomarker disease BEFREE Iron overload [serum ferritin (SF) ≥ 1500 ng/ml] was independently associated with TM (p = 0.001) and elevated serum hepcidin (p = 0.02). 28600663 2017
CUI: C0002875
Disease: Cooley's anemia
Cooley's anemia 		0.370 AlteredExpression disease BEFREE Peripheral expression of hepcidin gene in Egyptian β-thalassemia major. 25816754 2015
CUI: C0002875
Disease: Cooley's anemia
Cooley's anemia 		0.370 Biomarker disease BEFREE Hepcidin and other measured biochemical parameters were compared between the TM patients (100) and healthy children (37). 25923089 2015
CUI: C0002875
Disease: Cooley's anemia
Cooley's anemia 		0.370 GeneticVariation disease BEFREE Association of hepcidin promoter c.-582 A>G variant and iron overload in thalassemia major. 19734422 2009
CUI: C0002875
Disease: Cooley's anemia
Cooley's anemia 		0.370 AlteredExpression disease BEFREE In contrast, hepcidin levels were elevated in thalassemia major, presumably due to transfusions that reduce erythropoietic drive and deliver a large iron load. 17488680 2007
CUI: C0002875
Disease: Cooley's anemia
Cooley's anemia 		0.370 AlteredExpression disease BEFREE Significant down-regulation of hepcidin expression in beta-thalassemia major, despite iron overload, might explain the increased iron absorption typically observed in thalassemia. 16755567 2006
CUI: C0002875
Disease: Cooley's anemia
Cooley's anemia 		0.370 Biomarker disease CTD_human Significant down-regulation of hepcidin expression in beta-thalassemia major, despite iron overload, might explain the increased iron absorption typically observed in thalassemia. 16755567 2006
CUI: C0002875
Disease: Cooley's anemia
Cooley's anemia 		0.370 AlteredExpression disease BEFREE We evaluated the effect of iron overload and of ineffective erythropoeisis on hepcidin expression in patients with thalassemia major. 16769583 2006