BAX, BCL2 associated X, apoptosis regulator, 581

N. diseases: 420; N. variants: 9
Disease: Colorectal Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.060 Biomarker group LHGDN Potential role of apoptosis and apoptotic regulatory proteins in colorectal neoplasia: correlations with clinico-pathological parameters and survival. 17562177 2008
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.060 AlteredExpression group LHGDN Significant coexpression of GLUT-1, Bcl-xL, and Bax in colorectal cancer. 17404017 2007
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.060 AlteredExpression group LHGDN Connexin 26 correlates with Bcl-xL and Bax proteins expression in colorectal cancer. 15770735 2005
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.060 GeneticVariation group BEFREE Significance of mutations in TGFBR2 and BAX in neoplastic progression and patient outcome in sporadic colorectal tumors with high-frequency microsatellite instability. 15676142 2005
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.060 Biomarker group LHGDN Requirement of BAX for TRAIL/Apo2L-induced apoptosis of colorectal cancers: synergism with sulindac-mediated inhibition of Bcl-x(L). 11912124 2002
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.060 GeneticVariation group BEFREE The difference in the mutation spectrum of TGFBRII, BAX, and IGFIIR between brain and colorectal tumors in these individuals suggests that the mutator phenotype may target different pathogenic pathways in the oncogenic process of the two organs. 10337989 1999