RAB27B, RAB27B, member RAS oncogene family, 5874

N. diseases: 64; N. variants: 9
Disease: Mammary Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.030 AlteredExpression group BEFREE Consistent with previous studies, we here confirmed that Rab27B is upregulated in breast tumor tissue in comparison with normal breast tissue. 31002890 2019
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.030 AlteredExpression group BEFREE Poor prognosis ERα-positive primary breast tumors expressing high levels of Rab27B also expressed multiple V-ATPase subunits and showed a strong cytoplasmic and peripheral V-ATPase V1E expression. 23390068 2013
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.030 AlteredExpression group BEFREE Presence of endogenous Rab27B mRNA and protein, but not of Rab3D or Rab27A mRNA, was associated with lymph node metastasis (P < .001) and differentiation grade (P = .001) in ER-positive human breast tumors. 20484105 2010