RAD51B, RAD51 paralog B, 5890

N. diseases: 126; N. variants: 108
Disease: Uterine Fibroids ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042133
Disease: Uterine Fibroids
Uterine Fibroids 		0.040 AlteredExpression group BEFREE RAD51 paralog B (RAD51B), the preferential translocation partner of HMGA2, was up-regulated in MED12 mutant lesions, suggesting a role for this gene in the genesis of leiomyomas. 26787895 2016
CUI: C0042133
Disease: Uterine Fibroids
Uterine Fibroids 		0.040 Biomarker group BEFREE RAD51L1 is a tumor-suppressor gene belonging to the RAD51 family, already implicated in many tumors (uterine leiomyomas, pseudo-Meigs syndromes, pulmonary chondroid hamartomas) and involved in recombinational repair of DNA double-strand breaks. 15942943 2005
CUI: C0042133
Disease: Uterine Fibroids
Uterine Fibroids 		0.040 Biomarker group BEFREE Evidence for RAD51L1/HMGIC fusion in the pathogenesis of uterine leiomyoma. 11135437 2001
CUI: C0042133
Disease: Uterine Fibroids
Uterine Fibroids 		0.040 GeneticVariation group BEFREE Allelic knockout of novel splice variants of human recombination repair gene RAD51B in t(12;14) uterine leiomyomas. 9892177 1999