RANBP2, RAN binding protein 2, 5903

N. diseases: 110; N. variants: 57
Disease: Intervertebral disc disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0158252
Disease: Intervertebral disc disorder
Intervertebral disc disorder 		0.010 Biomarker group BEFREE The allelic variants in the collagen IX genes - COL9A2 (Trp2) and COL9A3 (Trp3) have been identified as genetic risk factors for IDD, because they interfere the cross-linking between collagen types II, IX and XI and result in decreased stability of intervertebral discs. 24636772 2014