RANBP2, RAN binding protein 2, 5903

N. diseases: 110; N. variants: 57
Disease: Tumor Immunity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1519680
Disease: Tumor Immunity
Tumor Immunity 		0.020 Biomarker phenotype BEFREE We used two mouse models of melanoma termed B16.OVA and B16-F10 for testing the efficacy of OVA SIINFEKL-peptide-coated viruses and gp100-Trp2-peptide-coated viruses, respectively, and show that by coating the viral envelope with therapeutic peptides, the anti-tumor immunity and the number of tumor-specific CD8<sup>+</sup> T cells in the tumor microenvironment can be significantly enhanced. 30005865 2018
CUI: C1519680
Disease: Tumor Immunity
Tumor Immunity 		0.020 Biomarker phenotype BEFREE In contrast to immunization against gp75(TRP-1), both tumor immunity and autoimmunity required CD8(+) T cells, but not antibodies. 10587362 1999