Disease: Primary gout ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0149896
Disease: Primary gout
Primary gout 		0.060 Biomarker disease BEFREE Our data indicate that MSU may activate TLR4, SYK, iNOS and TRPV1 to induce the release of IL-1β by macrophages, triggering nociception and inflammation during acute gout attack. 31298290 2020
CUI: C0149896
Disease: Primary gout
Primary gout 		0.060 GeneticVariation disease BEFREE Decreased Expression of CD14 in MSU-Mediated Inflammation May Be Associated with Spontaneous Remission of Acute Gout. 31312662 2019
CUI: C0149896
Disease: Primary gout
Primary gout 		0.060 Biomarker disease BEFREE Acute gout is an inflammatory response to MSU crystals. 31106362 2019
CUI: C0149896
Disease: Primary gout
Primary gout 		0.060 Biomarker disease BEFREE The translation of our knowledge of the biology of MSU crystal-induced IL-1 secretion gives rise to new targets and therapeutic strategies in the treatment of acute gout. 29272514 2018
CUI: C0149896
Disease: Primary gout
Primary gout 		0.060 Biomarker disease BEFREE This study showed that DNI was an effective independent marker to differentiate between an acute gout attack and cellulitis at the crucial early phase irrespective of MSU crystal confirmation or serum uric acid concentration. 28115599 2017
CUI: C0149896
Disease: Primary gout
Primary gout 		0.060 Biomarker disease BEFREE TREM-1 is induced by MSU and is associated with the inflammation of human acute gouty arthritis. 26320130 2016