Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.050 GeneticVariation disease BEFREE Our data demonstrated an independent or a joint effect of SMAD3 rs11556090 and RBL2 rs3929 in the cell cycle pathway on DFS of HCC, which need to be validated by large cohort and biological studies. 28639733 2017
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.050 Biomarker disease BEFREE However, p21(WAF1), p27(KIP1), p57(KIP), p130 and RassF1A proteins exhibited no change/low increase in the lesions of F344 rats and consistent rise in dysplastic nodules and HCC of BN rats. 19533683 2010
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.050 AlteredExpression disease BEFREE Of the four genes (CHD9, RBL2, AKTIP and RPGRIP1L) located in this region, only RPGRIP1L was downregulated in HCCs. 19410446 2009
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.050 Biomarker disease LHGDN Overexpression of tumour suppressor retinoblastoma 2 protein (pRb2/p130) in hepatocellular carcinoma. 15059924 2004
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.050 Biomarker disease LHGDN pRb2/p130, vascular endothelial growth factor, p27(KIP1), and proliferating cell nuclear antigen expression in hepatocellular carcinoma: their clinical significance. 15161709 2004