|
Partial chromosome Y deletion
|
0.300 |
GeneticVariation
|
phenotype |
ORPHANET |
Genetic dissection of the AZF regions of the human Y chromosome: thriller or filler for male (in)fertility?
|
20671934 |
2010 |
|
Male sterility due to Y-chromosome deletions
|
0.300 |
GeneticVariation
|
phenotype |
ORPHANET |
Genetic dissection of the AZF regions of the human Y chromosome: thriller or filler for male (in)fertility?
|
20671934 |
2010 |
|
Partial chromosome Y deletion
|
0.300 |
GeneticVariation
|
phenotype |
ORPHANET |
The human Y chromosome's azoospermia factor b (AZFb) region: sequence, structure, and deletion analysis in infertile men.
|
12525536 |
2003 |
|
Male sterility due to Y-chromosome deletions
|
0.300 |
GeneticVariation
|
phenotype |
ORPHANET |
The human Y chromosome's azoospermia factor b (AZFb) region: sequence, structure, and deletion analysis in infertile men.
|
12525536 |
2003 |
|
Spermatogenic Failure, Nonobstructive, Y-Linked
|
0.300 |
Biomarker
|
disease |
CTD_human |
|
|
|
|
Non-obstructive azoospermia
|
0.110 |
GeneticVariation
|
disease |
BEFREE |
To investigate the associations of autosomal and X-chromosome homologs of the RNA-binding-motif (RNA-binding-motif on the Y chromosome, RBMY) gene with non-obstructive azoospermia (NOA), as genetic factors for NOA may map to chromosomes other than the Y chromosome.
|
16491274 |
2006 |
|
Azoospermia
|
0.110 |
Biomarker
|
disease |
BEFREE |
Deletion of RBM and DAZ in azoospermia: evaluation by PRINS.
|
11807882 |
2002 |
|
Cryptorchidism
|
0.110 |
GeneticVariation
|
disease |
BEFREE |
Polymerase chain reaction (PCR) amplification of 51 DNA loci encompassing all of the regions for azoospermia factor (AZF) of the Y chromosome, including the deleted in azoospermia (DAZ) and ribonucleic acid-binding motif (RBM) genes, were examined for microdeletions in 10 PWS males with cryptorchidism and 20 healthy control male subjects.
|
11869370 |
2002 |
|
Oligospermia
|
0.110 |
Biomarker
|
disease |
BEFREE |
The RBM gene was deleted in two patients with Sertoli cell only who had particularly large deletions, but in no patients with arrest or hypospermatogenesis.
|
11532470 |
2001 |
|
Azoospermia
|
0.110 |
Biomarker
|
disease |
HPO |
|
|
|
|
Cryptorchidism
|
0.110 |
Biomarker
|
disease |
HPO |
|
|
|
|
Oligospermia
|
0.110 |
Biomarker
|
disease |
HPO |
|
|
|
|
Non-obstructive azoospermia
|
0.110 |
Biomarker
|
disease |
HPO |
|
|
|
|
Male infertility
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
|
Small testicle
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
|
Liver carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Although RNA binding motif (RBM) proteins are closely related to various cancers, the clinical importance and underlying mechanisms of RBM8A in HCC remain elusive.
|
28259942 |
2017 |
|
Breast Carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
The expression of mRNA corresponding to BRMS1, BCL2, BAX, CASP3 and the apoptosis-related X-chromosome RNA binding motif (RBM) genes (RBMX, RBM3, RBM10 small and large variant) was studied by means of differential RT-PCR in 94 samples obtained from previously untreated patients with breast carcinoma.
|
21737612 |
2011 |
|
Breast Carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
From these results, it seems that the X-chromosome, through its RBM genes, plays a formerly unknown role in the regulation of programmed cell death (apoptosis) in breast cancer.
|
16552754 |
2006 |
|
Liver carcinoma
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
HBV integrant of one HCC tissue (1217T) was integrated into a RNA binding motif Y chromosome (RBMY) gene.
|
12376959 |
2002 |
|
Myelodysplastic-Myeloproliferative Diseases
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Three patients were diagnosed with myelodysplastic/myeloproliferative neoplasm (MDS/MPN), while 61 revealed a "reactive" bone marrow ("RBM" group).
|
31102331 |
2019 |
|
MYELODYSPLASTIC SYNDROME
|
0.010 |
Biomarker
|
group |
BEFREE |
Statistical analysis revealed significant differences in Hb, RDW-CV%, NRBC%, and RET% values between the "MDS" and the "RBM" group.
|
31102331 |
2019 |
|
Eosinophilia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Airway inflammation (eosinophilic/neutrophilic) and remodeling were not present in wheezers at a mean age of 12 months, but in older pre-school children (mean 2.5 years), remodeling (mainly increased reticular basement membrane [RBM] thickness and increased area of airway smooth muscle) and also airway eosinophilia was reported.This was worse in school-age children.
|
29469196 |
2018 |
|
Adenocarcinoma of lung (disorder)
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, <i>RBM 10</i> mutation at exon 10 (c.763 C>T) occurs frequently and is an independent prognostic predictor in lung adenocarcinoma.
|
30405763 |
2018 |
|
Eosinophilic disorder
|
0.010 |
Biomarker
|
group |
BEFREE |
Airway inflammation (eosinophilic/neutrophilic) and remodeling were not present in wheezers at a mean age of 12 months, but in older pre-school children (mean 2.5 years), remodeling (mainly increased reticular basement membrane [RBM] thickness and increased area of airway smooth muscle) and also airway eosinophilia was reported.This was worse in school-age children.
|
29469196 |
2018 |
|
Thyroid carcinoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Vemurafenib-resistance via de novo RBM genes mutations and chromosome 5 aberrations is overcome by combined therapy with palbociclib in thyroid carcinoma with BRAF<sup>V600E</sup>.
|
29156680 |
2017 |