CCND1, cyclin D1, 595

N. diseases: 859; N. variants: 12
Disease: Precancerous Conditions ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032927
Disease: Precancerous Conditions
Precancerous Conditions 		0.330 AlteredExpression group BEFREE Cyclin D1 overexpression in basal and parabasal layers of epithelia distant from the invasion point may act as a potential marker of premalignant fields and multiple tumour development. 30321764 2019
CUI: C0032927
Disease: Precancerous Conditions
Precancerous Conditions 		0.330 Biomarker group BEFREE Here, we report that pregnant mice expressing an activated intracellular form of N3 (N3(IC)) exhibit a cyclin D1-dependent expansion of premalignant CD24(+) CD29(low) luminal progenitors with enhanced differentiation potential in vitro and in vivo. 23928992 2013
CUI: C0032927
Disease: Precancerous Conditions
Precancerous Conditions 		0.330 Biomarker group CTD_human Carcinogenicity of dimethylarsinic acid in male F344 rats and genetic alterations in induced urinary bladder tumors. 12151359 2002
CUI: C0032927
Disease: Precancerous Conditions
Precancerous Conditions 		0.330 AlteredExpression group BEFREE Overexpression of cyclin D1 was observed in 9/22 (41%) OSCC, 3/9 (33%) premalignant and 8/8 (100%) of OSCC cell lines. 10389982 1999