CCND1, cyclin D1, 595

N. diseases: 859; N. variants: 12
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0334037
Disease: Intestinal metaplasia
Intestinal metaplasia
0.020 GeneticVariation phenotype BEFREE CCND1 genotype was significantly associated with the severity of intestinal metaplasia by the Kruskal-Wallis test, and this tendency was especially stronger among older subjects of 61 years or older (overall subjects: p=0.035, 61 years approximately : p=0.007). 19055446 2008
CUI: C0334037
Disease: Intestinal metaplasia
Intestinal metaplasia
0.020 Biomarker phenotype BEFREE Positive nuclear staining for the cyclin D1 protein in Barrett's disease with intestinal metaplasia was found in 38% of the male cases and 25% of the female cases, whereas in gastric metaplasia it was positive in 33% of men and 48% of women. 8781742 1996