BCL2, BCL2 apoptosis regulator, 596

N. diseases: 1456; N. variants: 27
Disease: Intestinal metaplasia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0334037
Disease: Intestinal metaplasia
Intestinal metaplasia 		0.040 AlteredExpression phenotype BEFREE Levels of Bcl-2 were reduced in GC and AG/IM GC- compared to controls as well as in AG/IM GC- compared to AG/IM in mucosa adjacent to GC+ (p < 0.05). 28662697 2017
CUI: C0334037
Disease: Intestinal metaplasia
Intestinal metaplasia 		0.040 AlteredExpression phenotype BEFREE While no significant difference was determined between three groups with regard to apoptosis and Bcl-2 expression (p>0.05), Ki-67 expression was significantly higher in the IM group when compared with the CAG and NGM groups (29.90±22.87 vs. 18.18±16.22 vs. 18.54±20, respectively; p=0.012). 22277792 2012
CUI: C0334037
Disease: Intestinal metaplasia
Intestinal metaplasia 		0.040 AlteredExpression phenotype BEFREE Bcl-2 expression was correlated with the Lauren's classification (chi(2) = 4.725, P < 0.05), and the Bmi-1 expression both in GC (r(k) = 0.157, P < 0.05) and in intestinal metaplasia (r(k) = 0.270, P < 0.05). 19418588 2009
CUI: C0334037
Disease: Intestinal metaplasia
Intestinal metaplasia 		0.040 AlteredExpression phenotype BEFREE There was no correlation between bcl-2 expression and the presence of intestinal metaplasia (P = 0.35). 10219822 1999