RDX, radixin, 5962

N. diseases: 80; N. variants: 9
Disease: Neurofibromatosis 2 ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027832
Disease: Neurofibromatosis 2
Neurofibromatosis 2 		0.010 Biomarker disease BEFREE The NF2-encoded protein Merlin is closely related to the Ezrin-Radixin-Moesin family of membrane/cytoskeleton linker proteins, and has been demonstrated to suppress tumor growth by inhibiting extracellular signal-regulated kinase (ERK) and Rac1 activation. 18332868 2008