REG1A, regenerating family member 1 alpha, 5967

N. diseases: 264; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma
0.020 Biomarker disease BEFREE We demonstrate that short hairpin RNA mediated knockdown of full-length PTPµ and PTPµ fragments reduces glioma cell growth and survival in vitro. 22505657 2012
CUI: C0017638
Disease: Glioma
Glioma
0.020 Biomarker disease BEFREE These data suggest that PLCγ1 is downstream of PTPµ and that dephosphorylation of PLCγ1 is likely to be a major pathway through which PTPµ suppresses glioma cell migration. 20506511 2011