REG1A, regenerating family member 1 alpha, 5967

N. diseases: 264; N. variants: 2
Disease: Sjogren's Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.040 Biomarker disease BEFREE Recently, the presence of novel tissue specific autoantibodies (TSAs), SP-1, CA6, and PSP, has been observed in the early stages of SS. 30572137 2019
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.040 Biomarker disease BEFREE This dependence of REG Iα induction upon IL-6/STAT in salivary duct epithelial cells may play an important role in the pathogenesis/progression of Sjögren's syndrome. 27339601 2017
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.040 Biomarker disease BEFREE Several newly-identified biomarkers for SS include autoantibodies to proteins specific to the salivary and lacrimal glands [SP-1 (salivary gland protein-1), PSP (parotid secretory protein), CA-6 (carbonic anhydrase VI)]. 28283891 2017
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.040 Biomarker disease BEFREE Immunohistochemical staining for HTLV-1 p19 and tax was seen in 10 out of 33 (30.3%) patients with SS each. 22382336 2012