|
Kidney Diseases
|
0.400 |
Biomarker
|
group |
CTD_human |
Plasma norepinephrine levels were higher (p less than 0.01) and plasma renin activity lower (p less than 0.02) in the group with progression of renal disease.
|
6156352 |
1980 |
|
Kidney Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
Animal studies show that the renin-angiotensin system contributes to hypertension, glomerulosclerosis and progressive chronic renal failure in renal disease.
|
7700001 |
1994 |
|
Kidney Diseases
|
0.400 |
Biomarker
|
group |
CTD_human |
Prediction of renal impairment in elderly patients with congestive heart failure treated with captopril.
|
8723173 |
1996 |
|
Kidney Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
The renin-angiotensin-aldosterone (RAA) axis has been intensively evaluated for its contribution to cardiovascular disease and nephropathy.
|
8989734 |
1996 |
|
Kidney Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Examination of two genetic polymorphisms within the renin-angiotensin system: no evidence for an association with nephropathy in IDDM.
|
8877296 |
1996 |
|
Kidney Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
The renin-angiotensin system is likely to be important in the progression of renal diseases because of its effect on tissue hemodynamics and glomerular cell function.
|
8901844 |
1996 |
|
Kidney Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Thus, our data, in this large and ethnically homogeneous group of patients, do not support the hypothesis that these genetic variants of the renin-angiotensin system are strongly associated with either nephropathy or hypertension in patients with insulin-dependent or non-insulin-dependent diabetes mellitus.
|
9049480 |
1997 |
|
Kidney Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Genetics of the renin-angiotensin system and renal disease: a progress report.
|
9146976 |
1997 |
|
Kidney Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
As the intrarenal renin-angiotensin system might also be activated in this setting, we determined the ACE genotype together with other risk factors for the development of diabetic nephropathy in 122 patients with IDDM from a single centre with (n = 63) and without (n = 59) nephropathy.
|
9084972 |
1997 |
|
Kidney Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
As angiotensin II increases glomerular pressure, we studied the relationship between genetic polymorphisms in the renin-angiotensin system-angiotensin I converting enzyme (ACE), angiotensinogen (AGT), and angiotensin II, subtype 1, receptor-and the renal involvement of insulin-dependent diabetic subjects with proliferative retinopathy: those exposed to the risk of nephropathy due to diabetes.
|
9120002 |
1997 |
|
Kidney Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
The renin-angiotensin system is of crucial importance as a system for therapeutic intervention and as genetic marker for susceptibility to renal disease.
|
9407416 |
1997 |
|
Kidney Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
In the present study, we examined effects of renin-angiotensin system (RAS) on cardiac hypertrophy and renal disorders using Tsukuba hypertensive mice.
|
9607405 |
1998 |
|
Kidney Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
The aim of this study was to evaluate the role of the renin-angiotensin system (RAS) in cardiac hypertrophy and renal disorders in THMs.
|
9582107 |
1998 |
|
Kidney Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
Renin-angiotensin genes in renal development and the occurrence and progression of renal diseases.
|
10192247 |
1999 |
|
Kidney Diseases
|
0.400 |
AlteredExpression
|
group |
BEFREE |
Although the expression of renin and angiotensin-converting enzyme in experimental and human renal disease has been well characterized, no information is available regarding human angiotensin type 1 (AT1) receptor expression.
|
10073605 |
1999 |
|
Kidney Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
Renin-angiotensin system stimulates cardiac and renal disorders in Tsukuba hypertensive mice.
|
10081615 |
1999 |
|
Kidney Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
We determined various cardiovascular hormones of the renin-angiotensin system and angiotensin converting enzyme gene polymorphism in 56 patients with nondiabetic renal diseases who underwent a renal biopsy.
|
10100072 |
1999 |
|
Kidney Diseases
|
0.400 |
Biomarker
|
group |
BEFREE |
Plasma renin was increased in patients with nephropathy (median (range), 26.3 (5.2-243.3) vs 18.3 (4.2-373.5) microU/ml in the normoalbuminuric group, P<0.0001).
|
10462269 |
1999 |
|
Kidney Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Conflicting reports, mainly comparing affected with unaffected unrelated subjects, have suggested a possible role of some genotypes of the renin-angiotensin system in conferring nephropathy risk in type 2 diabetes.
|
10585308 |
1999 |
|
Kidney Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Genes that influence the renin-angiotensin system have been investigated in recent years as potential etiologic candidates of cardiovascular and renal diseases.
|
10567188 |
1999 |
|
Kidney Diseases
|
0.400 |
AlteredExpression
|
group |
BEFREE |
However, the renin angiotensin system, which is highly activated in malignant hypertension, is established as an important pathogenetic factor in different cardiovascular and renal diseases.
|
10855732 |
2000 |
|
Kidney Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The involvement of renin-angiotensin system (RAS) gene polymorphisms in the pathogenesis of nephropathy has been described predominantly in Caucasian populations.
|
11200871 |
2001 |
|
Kidney Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Role of genetic variability in the renin-angiotensin system in diabetic and nondiabetic renal disease.
|
11709806 |
2001 |
|
Kidney Diseases
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The renin-angiotensin system is important in the control of hemodynamic status and pathogenesis of macrovascular disease, which is a major cause of morbidity and mortality in patients with type 2 diabetes with nephropathy.
|
11431175 |
2001 |
|
Kidney Diseases
|
0.400 |
Biomarker
|
group |
CTD_human |
Immunosuppressive treatment protects against angiotensin II-induced renal damage.
|
12414515 |
2002 |