REN, renin, 5972

N. diseases: 721; N. variants: 25
Disease: Polycythemia Vera ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032463
Disease: Polycythemia Vera
Polycythemia Vera 		0.020 AlteredExpression disease BEFREE Bone marrow renin-angiotensin system expression in polycythemia vera and essential thrombocythemia depends on JAK2 mutational status. 17873518 2007
CUI: C0032463
Disease: Polycythemia Vera
Polycythemia Vera 		0.020 AlteredExpression disease BEFREE In this study, quantitative expression of the messenger RNAs of the major RAS components--angiotensin-converting enzyme (CD143), renin and angiotensinogen--were measured in BM samples by quantitative real-time polymerase chain reaction, to evaluate the activity of local BM RAS in polycythemia rubra vera (PV) in comparison with normal erythropoiesis. 16372584 2006