RHEB, Ras homolog, mTORC1 binding, 6009

N. diseases: 53; N. variants: 3
Disease: Liver carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.020 Biomarker disease BEFREE Integrated analysis of circRNA-100338, miR-141-3p, and target genes revealed that RHEB, a key regulator in mTOR signaling pathway, was the target of miR-141-3p in hepatitis B-related HCC. 31157168 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.020 AlteredExpression disease BEFREE <i>In vivo</i>, upon downregulation of RHEB expression, the tumorigenic ability of HCC significantly decreased (P<0.05). 29467900 2018