RNF2, ring finger protein 2, 6045

N. diseases: 63; N. variants: 1
Disease: HIV Infections ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0019693
Disease: HIV Infections
HIV Infections 		0.030 GeneticVariation group BEFREE These data provide evidence that the X-DING-CD4 gene contributes to early cellular protection from HIV infection in some individuals and this protection depends solely on the unique genetic regulation of the host. 22042911 2012
CUI: C0019693
Disease: HIV Infections
HIV Infections 		0.030 AlteredExpression group BEFREE In conclusion, results from this study show that the organism reacts to HIV-infection by an overexpression of DING proteins. 22427948 2012
CUI: C0019693
Disease: HIV Infections
HIV Infections 		0.030 Biomarker group BEFREE The X-DING-CD4-mediated inhibition of the IL-8 promoter also resulted in a reduction of the soluble IL-8 protein in endothelial cells and human macrophages infected with a subset of enteric bacteria frequently causing diarrhea in progressive HIV disease. 22031506 2012