BCL9, BCL9 transcription coactivator, 607

N. diseases: 74; N. variants: 12
Disease: Intestinal Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021841
Disease: Intestinal Neoplasms
Intestinal Neoplasms 		0.010 Biomarker group BEFREE Here, we confirm that TNKSi inhibit Wnt-induced transcription, similarly to carnosate, which reduces the transcriptional activity of β-catenin by blocking its binding to BCL9, and attenuates intestinal tumors in Apc(Min) mice. 24419084 2014