ROBO2, roundabout guidance receptor 2, 6092

N. diseases: 49; N. variants: 12
Disease: Vesico-Ureteral Reflux ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042580
Disease: Vesico-Ureteral Reflux
Vesico-Ureteral Reflux 		0.440 GeneticVariation disease BEFREE ROBO2 gene variants in children with primary nonsyndromic vesicoureteral reflux with or without renal hypoplasia/dysplasia. 27002985 2016
CUI: C0042580
Disease: Vesico-Ureteral Reflux
Vesico-Ureteral Reflux 		0.440 GeneticVariation disease BEFREE Heterozygous non-synonymous ROBO2 variants are unlikely to be sufficient to cause familial vesicoureteric reflux. 23536131 2013
CUI: C0042580
Disease: Vesico-Ureteral Reflux
Vesico-Ureteral Reflux 		0.440 GeneticVariation disease BEFREE Recently, two heterozygous ROBO2 missense mutations were identified in two families with primary vesicoureteral reflux occurring in combination with congenital anomalies of the kidney and urinary tract (VUR/CAKUT). 18235093 2008
CUI: C0042580
Disease: Vesico-Ureteral Reflux
Vesico-Ureteral Reflux 		0.440 GeneticVariation disease LHGDN Recently, two heterozygous ROBO2 missense mutations were identified in two families with primary vesicoureteral reflux occurring in combination with congenital anomalies of the kidney and urinary tract (VUR/CAKUT). 18235093 2008
CUI: C0042580
Disease: Vesico-Ureteral Reflux
Vesico-Ureteral Reflux 		0.440 Biomarker disease LHGDN Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux. 17357069 2007
CUI: C0042580
Disease: Vesico-Ureteral Reflux
Vesico-Ureteral Reflux 		0.440 Biomarker disease BEFREE Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux. 17357069 2007
CUI: C0042580
Disease: Vesico-Ureteral Reflux
Vesico-Ureteral Reflux 		0.440 Biomarker disease GENOMICS_ENGLAND
CUI: C0042580
Disease: Vesico-Ureteral Reflux
Vesico-Ureteral Reflux 		0.440 Biomarker disease HPO