BCR, BCR activator of RhoGEF and GTPase, 613

N. diseases: 392; N. variants: 7
Disease: Burkitt Lymphoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma 		0.340 Biomarker disease BEFREE Oligonucleotide sets that probe breakpoints of <i>IGH-BCL2</i> (immunoglobulin heavy-apoptosis regulator) in follicular lymphoma (FL), <i>MYC-IGH</i> (MYC proto-oncogene, bHLH transcription factor-immunoglobulin heavy) in Burkitt lymphoma (BL) and <i>BCR-ABL1</i> (RhoGEF and GTPase activating protein-ABL proto-oncogene 1, non-receptor tyrosine kinase) in chronic myelogenous leukemia (CML) were designed. 28515100 2017
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma 		0.340 FusionGene disease ORPHANET Simultaneous occurrence of ETV6-RUNX1 and BCR-ABL1 (e1a2) transcripts in a child with B-cell acute lymphoblastic leukemia. 23491079 2013
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma 		0.340 Biomarker disease BEFREE BimL upregulation induced by BCR cross-linking in BL41 Burkitt's lymphoma results from a splicing mechanism of the BimEL mRNA. 19332026 2009
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma 		0.340 AlteredExpression disease BEFREE Altered gene expression upon BCR cross-linking in Burkitt's lymphoma B cell line. 11027651 2000
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma 		0.340 GeneticVariation disease BEFREE Thus, at the molecular level, DGS-related breakpoints can be distinguished from the 22q11 breakpoint of CML, but not from the 8;22 translocation of Burkitt lymphoma or from the 21;22 translocations that we have previously studied. 3930157 1985