RYR2, ryanodine receptor 2, 6262

N. diseases: 160; N. variants: 116
Disease: Induced ventricular tachycardia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0340486
Disease: Induced ventricular tachycardia
Induced ventricular tachycardia 		0.030 GeneticVariation disease BEFREE CPVT was diagnosed in probands with symptoms and stress- or adrenaline-provoked VT, or in asymptomatic relatives with provoked VT or RyR2 mutations. 21315846 2011
CUI: C0340486
Disease: Induced ventricular tachycardia
Induced ventricular tachycardia 		0.030 Biomarker disease BEFREE These findings may have profound consequences for the therapeutic modulation of RyR2 in stress-induced VT and SCD. 15364613 2004
CUI: C0340486
Disease: Induced ventricular tachycardia
Induced ventricular tachycardia 		0.030 AlteredExpression disease BEFREE Enhanced basal activity of RyR2 may underlie an arrhythmogenic mechanism for effort-induced ventricular tachycardia. 12169647 2002