S100A8, S100 calcium binding protein A8, 6279

N. diseases: 369; N. variants: 2
Disease: Myocardial rupture ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018813
Disease: Myocardial rupture
Myocardial rupture 		0.010 AlteredExpression disease BEFREE S100A8/A9 induced the activation of NF-κB and expression of MMP-9 protein in HCF cells through facilitating secretion of TNFα from macrophages, which may play a role in triggering extracellular matrix degradation and CR. 29949169 2018