Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.040 GeneticVariation disease BEFREE These data suggest that rare variant p.Gly8Ser of SCN4B confers a significant risk of AF, and SCN4B is a candidate susceptibility gene for AF. 30821358 2019
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.040 Biomarker disease BEFREE To the best of our knowledge, this is the first study to demonstrate an association of SCN4B mutations with AF, suggesting SCN4B as a novel AF susceptibility gene. 23604097 2013
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.040 GeneticVariation disease BEFREE We tested the hypothesis that lone AF in young patients is associated with genetic mutations in SCN3B and SCN4B, the genes encoding the two β-subunits of the cardiac sodium channel. 21051419 2011
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation
0.040 GeneticVariation disease BEFREE We tested the hypothesis that mutations in the 4 sodium channel beta-subunit genes SCN1B-SCN4B contribute to AF susceptibility. 19808477 2009