|
Parkinsonian Disorders
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Elevated levels of pro-inflammatory RANTES or MCP-1 and decreased levels of anti-inflammatory IL-10 were found to associate with Parkinsonism and a more rapid disease progression, indicated by longitudinal measurements of either MMSE or ADCS-ADL decline.
|
31559531 |
2020 |
|
early pregnancy
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
In the present study, we described the potential role of porcine CCL5 in embryo implantation and fetal-maternal environment during early pregnancy.
|
31563460 |
2020 |
|
Adenoma
|
0.010 |
GeneticVariation
|
group |
BEFREE |
We identified that tumor-derived cytokine CCL5 is upregulated in AIP-mutation-positive human adenomas.
|
30867568 |
2019 |
|
Anemia, Sickle Cell
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In addition, levels of IP-10 were higher in pregnant women with sickle cell disease and, interestingly, RANTES levels were higher in normal pregnancy when compared to pregnancy in sickle cell disease.
|
30006250 |
2019 |
|
Mental Depression
|
0.010 |
Biomarker
|
disease |
BEFREE |
Apolipoprotein A-II was also associated with FSS (P = .022). sNfL, CCL5, CCL18, sICAM-1, and sVCAM-1 levels were not associated with fatigue after adjusting for disability and depression.
|
31307953 |
2019 |
|
Depressive disorder
|
0.010 |
Biomarker
|
disease |
BEFREE |
Apolipoprotein A-II was also associated with FSS (P = .022). sNfL, CCL5, CCL18, sICAM-1, and sVCAM-1 levels were not associated with fatigue after adjusting for disability and depression.
|
31307953 |
2019 |
|
Fatigue
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Apolipoprotein A-II was also associated with FSS (P = .022). sNfL, CCL5, CCL18, sICAM-1, and sVCAM-1 levels were not associated with fatigue after adjusting for disability and depression.
|
31307953 |
2019 |
|
Fibrodysplasia Ossificans Progressiva
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
There appeared a rather clear-cut signal of a 2-fold higher level of CCL5 in the FOP patient vs. the healthy subject and the van Buchem patient.
|
31443758 |
2019 |
|
Heart failure
|
0.010 |
Biomarker
|
disease |
BEFREE |
ASB14 may be involved in HF progression via protein ubiquitination and CCL5 may be involved in HF via the IRF1-CCL5 interaction.
|
30370655 |
2019 |
|
Congestive heart failure
|
0.010 |
Biomarker
|
disease |
BEFREE |
ASB14 may be involved in HF progression via protein ubiquitination and CCL5 may be involved in HF via the IRF1-CCL5 interaction.
|
30370655 |
2019 |
|
Severe Dengue
|
0.010 |
Biomarker
|
disease |
BEFREE |
An elevated levels of cytokines IL6 and IL10 chemokine IL8 and CXCL10 along with decreased RANTES were found in the patients with Severe Dengue as compared to mild forms of dengue (p < 0.0001) during 3-6 days of infections.
|
30395811 |
2019 |
|
Kidney Failure, Acute
|
0.010 |
Biomarker
|
disease |
BEFREE |
Compared to wild-type (WT) mice with a renal IRI, IL-10 knockout (IL-10 KO) mice with IRI demonstrated decreased renal function as represented by blood urea nitrogen and serum creatinine, upregulated early acute kidney injury (AKI) biomarkers such as kidney injury molecule-1 (Kim-1), increased mRNA expression of the pro-inflammatory cytokines IL-1β, IL-6, and IL-18 and a chemokine (regulated on activation, normal T cell expressed and secreted; RANTES), and increased expression of the pro-apoptosis factors Bax and cleaved caspase-3.
|
30700847 |
2019 |
|
Mycoplasma pneumonia
|
0.010 |
Biomarker
|
disease |
BEFREE |
These results indicated that CCL5 may be involved in the progression of MPP, and hyperoside was beneficial for MPP probably through CCL5-CCR4 interactions, which may provide a potential effective therapy for MPP.
|
30350306 |
2019 |
|
Pulmonary Eosinophilia
|
0.010 |
Biomarker
|
disease |
BEFREE |
Although several chemokines, including eotaxin-1 (CCL11), RANTES (CCL5) and macrophage inflammatory protein 1β (MIP-1β or CCL4), have been detected in bronchoalveolar lavage fluid (BALF) from patients with EP, the pathophysiological mechanisms underlying EP, including potential relationships between eosinophils and CCL4, have not been fully elucidated.
|
30854716 |
2019 |
|
Thrombocytopenia
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Even though the degree of thrombocytopenia and platelet activation were similar between dengue-infected and HIV plus dengue-coinfected patients, plasma levels of the platelet-derived chemokines RANTES/CCL5 and PF4/CXCL4 were lower in coinfection.
|
31068600 |
2019 |
|
Upper Respiratory Infections
|
0.010 |
Biomarker
|
group |
BEFREE |
NOP children had higher levels of IL-6 (P = .02), IL-10 (P = .02), interferon-γ (P = .003), TNF-α (P = .006), IL-1β (P = .022), monocyte chemoattractant protein 1 (P = .028), RANTES (P = .005), IL-2 (P = .002), and IL-17 (P = .007) during viral URIs versus AOMs following the URIs, when compared to sOP children.
|
30188973 |
2019 |
|
Complete atrioventricular block
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Increasing serum level of CCL5 in CHB patients was severely associated with disease progression.
|
31200663 |
2019 |
|
Periosteal Disorder
|
0.010 |
Biomarker
|
disease |
BEFREE |
Thus, the adult periosteum maintains genetically distinct SSC subsets with a CCL5-dependent migratory mechanism required for bone maintenance and injury repair.
|
31809737 |
2019 |
|
Ki-1+ Anaplastic Large Cell Lymphoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In patients with ALK<sup>-</sup> anaplastic large cell lymphoma, 9 cytokines showed a prognostic impact, with higher levels of interferon γ, interleukin (IL)-8, IL-10, IL-17, IL-23, IP-10, monocyte chemoattractant protein-1, macrophage inflammatory protein-1β, and RANTES negatively affecting clinical outcomes.
|
30327172 |
2019 |
|
Renal interstitial fibrosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Besides, their gene expression levels were found significantly positive correlation with the degree of RIF (CD2: P<0.05, r=0.29; CCL5: P<0.05, r=0.31; CCR5: P<0.05, r=0.38).
|
31700890 |
2019 |
|
Viral Encephalitis
|
0.010 |
Biomarker
|
group |
BEFREE |
CCL2 and CCL5 along with TLR7 may be associated with degree of pathogenesis of JE and could be putative therapeutic targets for preventing severe inflammation during viral encephalitis.
|
30585774 |
2019 |
|
Coinfection
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Even though the degree of thrombocytopenia and platelet activation were similar between dengue-infected and HIV plus dengue-coinfected patients, plasma levels of the platelet-derived chemokines RANTES/CCL5 and PF4/CXCL4 were lower in coinfection.
|
31068600 |
2019 |
|
Zika Virus Infection
|
0.010 |
Biomarker
|
disease |
BEFREE |
A total of 125 Vero cell host proteins, including cytokines such as CXCL11 and CCL5, interferon stimulated gene 15, and translation initiation factors EIF5A and EIF4G2, are significantly dysregulated after ZIKV infection.
|
30578658 |
2019 |
|
Adenocarcinoma Of Esophagus
|
0.010 |
Biomarker
|
disease |
BEFREE |
Despite the abundance of Th1 chemokines RANTES (CCL5) and MIP-1α (CCL3) in OAC tumour, enrichments of intratumoural T cells expressing corresponding receptors were not observed.
|
30834503 |
2019 |
|
Hyperplastic Polyp
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In vitro, M. pneumoniae (MP) infection to A549 cells induced the expression of CCL5, chemokines receptor 4 (CCR4), nuclear factor-κB (NF-κB) nuclear protein, and phosphorylation of NF-κB-p65 (p-NF-κB-p65), whereas NF-κB cytoplasmic protein was decreased.
|
30350306 |
2019 |