CCL5, C-C motif chemokine ligand 5, 6352

N. diseases: 514; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0275518
Disease: Acute infectious disease
Acute infectious disease
0.020 Biomarker group BEFREE However, defects in RANTES or RANTES receptors including CCR5 can compromise immunity to acute infections in animal models and lead to more severe disease in humans infected with west Nile virus (WNV). 21814510 2011
CUI: C0275518
Disease: Acute infectious disease
Acute infectious disease
0.020 Biomarker group BEFREE Rhesus macaques were susceptible to SHIV(89.6-MIP-1alpha), SHIV(89.6-RANTES), SHIV(89.6-LTN), and nef-deleted control SHIV(89.6-dLTN) infection via the intrarectal route using standard virus doses, and intact viruses were reisolated from infected animals throughout the interval of acute infection. 12725687 2003