CCL17, C-C motif chemokine ligand 17, 6361

N. diseases: 162; N. variants: 4
Disease: Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3658302
Disease: Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum
Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum 		0.010 AlteredExpression disease BEFREE These results suggest that APN inhibits TNF-α- and IFN-γ-induced TARC/CCL17 and MDC/CCL22 production through downregulation of p38 MAPK and NF-κB signaling, resulting in the sparse distribution of Tregs in the skin of patients with APN-associated Stevens-Johnson syndrome/toxic epidermal necrolysis. 28949055 2018