CX3CL1, C-X3-C motif chemokine ligand 1, 6376

N. diseases: 243; N. variants: 6
Disease: Degenerative polyarthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.040 Biomarker disease BEFREE And DC32 significantly inhibited the invasion and migration of cultured OA-FLSs, as well as the transcription of IL-6, IL-1β, CXCL12 and CX3CL1 in cultured OA-FLSs measured by qPCR. 31228817 2019
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.040 Biomarker disease BEFREE The relationship between CX3CL1 and MMPs in the pathophysiology of OA is still unclear. 29268768 2017
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.040 Biomarker disease BEFREE It is the first time to show that TRAF1, CTGF, and CX3CL1 genes were hypomethylated in OA chondrocytes and have a consistent correlation with mRNA expression, which suggests that epigenetic changes in the methylation status of TRAF1, CTGF, and CX3CL1 contribute to the pathology of OA. 28470428 2017
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.040 Biomarker disease BEFREE The importance of CX3CL1/CX3CR1 signalling in the pathophysiology of OA is still under investigation. 24556958 2014