SDC4, syndecan 4, 6385

N. diseases: 71; N. variants: 1
Disease: Heart failure ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018801
Disease: Heart failure
Heart failure 		0.040 AlteredExpression disease BEFREE Increased syndecan-4 levels were previously detected after acute myocardial infarction and in subjects with heart failure. 29232393 2017
CUI: C0018801
Disease: Heart failure
Heart failure 		0.040 Biomarker disease BEFREE Our data suggest that syndecan-4 is essential for the compensated hypertrophy and the maintenance of cardiac function during the process of heart failure following pressure overload. 28395201 2017
CUI: C0018801
Disease: Heart failure
Heart failure 		0.040 Biomarker disease BEFREE Circulating shed syndecan-4 is increased in heart failure patients, however the pathophysiological and molecular consequences associated with syndecan-4 shedding remain poorly understood. 26449522 2015
CUI: C0018801
Disease: Heart failure
Heart failure 		0.040 Biomarker disease BEFREE Syndecan-4, a transmembrane heparan sulfate proteoglycan, is essential for pathological remodeling, and we here investigated its expression and shedding during heart failure. 23374111 2013