DisGeNET - a database of gene-disease associations

BLK, BLK proto-oncogene, Src family tyrosine kinase, 640

N. diseases: 86; N. variants: 57

Disease: Encephalitis, St. Louis ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Disease

Score _gda

Association Type

Type

Original DB

Sentence supporting the association

PMID

PMID Year

CUI:	C0014060
Disease:	Encephalitis, St. Louis

Encephalitis, St. Louis

0.030

GeneticVariation

disease

BEFREE

BLK pathway-associated rs13277113 GA genotype is more frequent in SLE patients and associated with low gene expression and increased flares.

27864698

2017

CUI:	C0014060
Disease:	Encephalitis, St. Louis

Encephalitis, St. Louis

0.030

GeneticVariation

disease

BEFREE

The association of the BLK gene with SLE was replicated in Chinese Han.

20130895

2010

CUI:	C0014060
Disease:	Encephalitis, St. Louis

Encephalitis, St. Louis

0.030

Biomarker

disease

BEFREE

Population differences in SLE susceptibility genes: STAT4 and BLK, but not PXK, are associated with systemic lupus erythematosus in Hong Kong Chinese.

19225526

2009