SELPLG, selectin P ligand, 6404

N. diseases: 113; N. variants: 1
Disease: Coronary heart disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.050 GeneticVariation disease BEFREE The present study demonstrated no evidence of association between individual SELP or PSGL-1 SNPs or haplotypes with incident CHD. 20376705 2011
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.050 GeneticVariation disease BEFREE PSGL-1 genotypes carrying the 62I allele were significantly protective for incident CHD (HRR 0.53, 95%CI 0.31-0.92, P=0.02) and ischemic stroke (HRR 0.73, 95%CI 0.55-0.97, P=0.03) in African Americans. 17420019 2007
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.050 GeneticVariation disease LHGDN We tested the association of four PSEL and two PSGL-1 polymorphisms with incident coronary heart disease (CHD) and ischemic stroke among 13,875 participants in the prospective Atherosclerosis Risk in Communities (ARIC) study. 17420019 2007
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.050 Biomarker disease BEFREE Polymorphisms in the P-selectin (CD62P) and P-selectin glycoprotein ligand-1 (PSGL-1) genes and coronary heart disease. 15497463 2004
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.050 GeneticVariation disease BEFREE SELPLG gene polymorphisms in relation to plasma SELPLG levels and coronary artery disease. 14641238 2003
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease 		0.050 GeneticVariation disease BEFREE These results demonstrate that the PSGL-1 VNTR polymorphism is not a genetic risk factor for CHD. 12879153 2003