SELPLG, selectin P ligand, 6404

N. diseases: 113; N. variants: 1
Disease: Hypertensive disease ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.050 Biomarker group BEFREE PSGL1-deficient mice develop spontaneous pulmonary hypertension associated to systemic sclerosis. 31509349 2020
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.050 Biomarker group BEFREE Our results indicate that PSGL-1 is involved in the development of salt-sensitive hypertension via vascular inflammation and injury. 29541444 2018
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.050 Biomarker group BEFREE Angiotensin II-induced Hypertension is Reduced by Deficiency of P-selectin Glycoprotein Ligand-1. 29459637 2018
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.050 AlteredExpression group BEFREE Hypertension is associated with increased expression of FABP3, FAS, FN1, IL1R2, LPL, SERPINE1, TGFB1, and VCAM1 and decreased expression of SELPLG and SERPINEB2. 23337395 2014
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.050 GeneticVariation group BEFREE The role of the PSGL-1 polymorphism was also evaluated according to the additional risk factors of age, sex, smoking history, hypertension, hypercholesterolemia, and diabetes. 15459589 2004