SELPLG, selectin P ligand, 6404

N. diseases: 113; N. variants: 1
Disease: Ischemic stroke ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.030 GeneticVariation disease BEFREE Correlations of platelet-leukocyte aggregates with P-selectin S290N and P-selectin glycoprotein ligand-1 M62I genetic polymorphisms in patients with acute ischemic stroke. 27423570 2016
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.030 GeneticVariation disease BEFREE The association of SNP rs2228315 in the P-Selectin Glycoprotein Ligand-1-gene (PSGL1) with ischemic stroke and platelet activation was significant before correction for multiple testing while a trend was observed for the association with PLA. 25720421 2015
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.030 GeneticVariation disease BEFREE PSGL-1 genotypes carrying the 62I allele were significantly protective for incident CHD (HRR 0.53, 95%CI 0.31-0.92, P=0.02) and ischemic stroke (HRR 0.73, 95%CI 0.55-0.97, P=0.03) in African Americans. 17420019 2007