Disease: Uveal melanoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0220633
Disease: Uveal melanoma
Uveal melanoma 		0.030 Biomarker disease BEFREE Here, we determine the functional role of p63 expression in the initiation of p53/PERP-mediated apoptosis in UM. 27584665 2016
CUI: C0220633
Disease: Uveal melanoma
Uveal melanoma 		0.030 AlteredExpression disease BEFREE Downregulation of PERP is associated with the aggressive, monosomy 3-type of uveal melanoma (UM), the most common primary intraocular tumour in adults, and increased PERP expression has a pro-apoptotic effect in UM cells. 21451571 2011
CUI: C0220633
Disease: Uveal melanoma
Uveal melanoma 		0.030 Biomarker disease BEFREE The altered expression of PERP highlighted this apoptosis-specific target of p53 as a possible contributor to apoptosis in uveal melanoma with PERP downregulation being particularly relevant to the aggressive (monosomy 3) type of uveal melanoma. 16784742 2006