Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524528
Disease: Pervasive Development Disorder
Pervasive Development Disorder 		0.010 GeneticVariation group BEFREE Based on genetic analyses we identified mutations in LIN-7B gene in some ASD (autism-spectrum disorder) patients. 25196215 2015
CUI: C1510586
Disease: Autism Spectrum Disorders
Autism Spectrum Disorders 		0.010 Biomarker disease BEFREE Taken together, Lin-7B was found to play a pivotal role in corticogenesis through the regulation of excitatory neuron migration and interhemispheric axon growth, while further analyses are required to directly link functional defects of Lin-7B to ASD pathophysiology. 25196215 2015
CUI: C1837249
Disease: Malformations of Cortical Development, Group II
Malformations of Cortical Development, Group II 		0.010 Biomarker disease BEFREE Functional defects in Lin-7B caused abnormal neuronal migration and interhemispheric axon growth during mouse brain development. 25196215 2015
CUI: C0020179
Disease: Huntington Disease
Huntington Disease 		0.010 Biomarker disease BEFREE Decreases in LIN7B and CNTN1 RNAs were also detected in human HD layer 5 motor cortex neurons. 20720508 2010