SFRP2, secreted frizzled related protein 2, 6423

N. diseases: 134; N. variants: 0
Disease: Tumor Progression ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.020 PosttranslationalModification phenotype BEFREE Furthermore, SFRP2 methylation was shown to accelerate cancer cell invasion and growth in tumor progression. 28273499 2017
CUI: C0178874
Disease: Tumor Progression
Tumor Progression 		0.020 PosttranslationalModification phenotype BEFREE Linear mixed-effects modelling was used in this study to understand the onset and patterns of the methylation changes of SFRP2, IGF2 DMR0, H19, LINE-1 and a CpG island methylator phenotype (CIMP) marker panel, and they were correlated with DNA methyltransferase 3B (DNMT3B) levels of expression in a sample set representative of colorectal neoplastic progression. 21068132 2011