SFTPD, surfactant protein D, 6441

N. diseases: 194; N. variants: 12
Disease: Obesity ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity 		0.040 Biomarker disease BEFREE Interestingly, SP-D deficiency worsened hypercholesterolemia and induced obesity and insulin resistance but suppressed plasma interleukin-6 (IL-6) levels. 28472244 2017
CUI: C0028754
Disease: Obesity
Obesity 		0.040 Biomarker disease BEFREE Serum Surfactant Protein D as a Biomarker for Measuring Lung Involvement in Obese Patients With Type 2 Diabetes. 28945872 2017
CUI: C0028754
Disease: Obesity
Obesity 		0.040 Biomarker disease BEFREE Changes in genetic variations affecting the taste receptor, type 2, member 38 (TAS2R38) may identify the interacting mechanism leading to obesity and potential associations with proteins partaking in innate immunity, such as surfactant protein D (SPD) and mannan-binding lectin (MBL). 27059147 2016
CUI: C0028754
Disease: Obesity
Obesity 		0.040 Biomarker disease BEFREE Surfactant protein D of the innate immune defence is inversely associated with human obesity and SP-D deficiency infers increased body weight in mice. 17083619 2006