TPSB2, tryptase beta 2 (gene/pseudogene), 64499

N. diseases: 11; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0022548
Disease: Keloid
Keloid 		0.300 Biomarker disease CTD_human Comparative proteomic analysis between normal skin and keloid scar. 20128793 2010
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement 		0.100 GeneticVariation phenotype GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.020 GeneticVariation group BEFREE PD-L1 status was defined as: 1) PD-L1 high (tumor proportion score, TPS≥50%), PD-L1 low (TPS 1-49%), PD-L1 negative (TPS<1%); 2) PD-L1 positive (TPS≥50%) and negative (TPS<50%); 3) as a continuous variable. 30728907 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.020 Biomarker group BEFREE The PD-L1 expression was determined by the Tumor Proportion Score (TPS) and classified into TPS <1%, TPS 1 to 49% and TPS ≥50%. 29137398 2017
CUI: C4280806
Disease: Calcium oxalate kidney stones
Calcium oxalate kidney stones 		0.010 Biomarker disease BEFREE <b>Conclusion:</b> These results suggest that tea polysaccharides, especially TPS2, may inhibit the formation and recurrence of calcium oxalate kidney stones. 31239679 2019
CUI: C0022650
Disease: Kidney Calculi
Kidney Calculi 		0.010 AlteredExpression disease BEFREE TPS2, with moderate Mw, showed the strongest antioxidant activity and repair effect; it may become a potential drug for prevention and treatment of kidney stones. 30584463 2018
CUI: C0392525
Disease: Nephrolithiasis
Nephrolithiasis 		0.010 AlteredExpression disease BEFREE TPS2, with moderate Mw, showed the strongest antioxidant activity and repair effect; it may become a potential drug for prevention and treatment of kidney stones. 30584463 2018
CUI: C0011195
Disease: Dejerine-Sottas Disease (disorder)
Dejerine-Sottas Disease (disorder) 		0.010 GeneticVariation disease BEFREE Alpha tryptase allele of Tryptase 1 (TPSAB1) gene associated with Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS) in Vietnam and Philippines. 25797204 2015
CUI: C0019100
Disease: Severe Dengue
Severe Dengue 		0.010 GeneticVariation disease BEFREE Alpha tryptase allele of Tryptase 1 (TPSAB1) gene associated with Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS) in Vietnam and Philippines. 25797204 2015
CUI: C0376300
Disease: Dengue Shock Syndrome
Dengue Shock Syndrome 		0.010 GeneticVariation disease BEFREE Alpha tryptase allele of Tryptase 1 (TPSAB1) gene associated with Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS) in Vietnam and Philippines. 25797204 2015
CUI: C1848296
Disease: DOSAGE-SENSITIVE SEX REVERSAL
DOSAGE-SENSITIVE SEX REVERSAL 		0.010 GeneticVariation disease BEFREE Alpha tryptase allele of Tryptase 1 (TPSAB1) gene associated with Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS) in Vietnam and Philippines. 25797204 2015
CUI: C0024899
Disease: Mastocytosis
Mastocytosis 		0.010 GeneticVariation disease LHGDN Tryptase haplotype in mastocytosis: relationship to disease variant and diagnostic utility of total tryptase levels. 17449330 2007