SH3BP2, SH3 domain binding protein 2, 6452

N. diseases: 65; N. variants: 7
Disease: Arthritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003864
Disease: Arthritis
Arthritis 		0.020 GeneticVariation disease BEFREE We had previously reported that a gain-of-function mutation in SH3BP2 exacerbates inflammation and bone loss in murine arthritis models. 31052273 2019
CUI: C0003864
Disease: Arthritis
Arthritis 		0.020 Biomarker disease BEFREE Second, CIA was induced in Sh3bp2(-/-) and Sh3bp2(+/+) mice, and the incidence and severity of arthritis were evaluated. 25470448 2015