ITSN1, intersectin 1, 6453

N. diseases: 51; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma
0.030 Biomarker disease BEFREE In this study, we first confirmed that ITSN1-L exerted an inhibitory role in glioma progression both in vivo and in vitro, which was contrary to the function of ITSN1-S. 31160551 2019
CUI: C0017638
Disease: Glioma
Glioma
0.030 AlteredExpression disease BEFREE We discovered that ITSN1-S expression was positively correlated with histological grade of gliomas and with poor patient prognosis. 25832561 2015
CUI: C0017638
Disease: Glioma
Glioma
0.030 AlteredExpression disease BEFREE In this study, we show that siRNA-mediated down regulation of ITSN1-s induced glioma cells apoptosis. 20493827 2010