|
Tumor Cell Invasion
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
Meanwhile, lncRNA-TPTE2P1 stimulated HCC cell migration and invasion by promoting EMT.
|
31114999 |
2019 |
|
Tumor Cell Invasion
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
In this study, the roles of the lncRNA transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 1 (TPTE2P1), previously implicated in gallbladder cancer cell migration and invasion, were evaluated in CRC.
|
30382596 |
2019 |
|
Tumor Cell Invasion
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
We figured that depletion of TPTE2P1 remarkably inhibited gallbladder cancer cell migration and invasion capacity in vitro and elevated the expression of β-catenin via epithelial-mesenchymal transition signalling.
|
25676706 |
2015 |
|
Neoplasms
|
0.020 |
AlteredExpression
|
group |
BEFREE |
Further analysis revealed that overexpression of lncRNA-TPTE2P1 was correlated with tumor size, distant metastasis, differentiation degree, as well as tumor node metastasis (TNM) stage of HCC patients.
|
31114999 |
2019 |
|
Neoplasms
|
0.020 |
AlteredExpression
|
group |
BEFREE |
TPTE2P1 is upregulated in CRC and plays essential roles in the regulation of cell viability in vitro and tumor formation in vivo.
|
30382596 |
2019 |
|
Malignant neoplasm of gallbladder
|
0.020 |
Biomarker
|
disease |
BEFREE |
In this study, the roles of the lncRNA transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 1 (TPTE2P1), previously implicated in gallbladder cancer cell migration and invasion, were evaluated in CRC.
|
30382596 |
2019 |
|
Gallbladder Carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
In this study, the roles of the lncRNA transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 1 (TPTE2P1), previously implicated in gallbladder cancer cell migration and invasion, were evaluated in CRC.
|
30382596 |
2019 |
|
Stage 0 Gallbladder Cancer AJCC v8
|
0.020 |
Biomarker
|
disease |
BEFREE |
In this study, the roles of the lncRNA transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 1 (TPTE2P1), previously implicated in gallbladder cancer cell migration and invasion, were evaluated in CRC.
|
30382596 |
2019 |
|
Stage IIA Gallbladder Cancer AJCC v8
|
0.020 |
Biomarker
|
disease |
BEFREE |
In this study, the roles of the lncRNA transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 1 (TPTE2P1), previously implicated in gallbladder cancer cell migration and invasion, were evaluated in CRC.
|
30382596 |
2019 |
|
Stage IIB Gallbladder Cancer AJCC v8
|
0.020 |
Biomarker
|
disease |
BEFREE |
In this study, the roles of the lncRNA transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 1 (TPTE2P1), previously implicated in gallbladder cancer cell migration and invasion, were evaluated in CRC.
|
30382596 |
2019 |
|
Stage III Gallbladder Cancer AJCC v8
|
0.020 |
Biomarker
|
disease |
BEFREE |
In this study, the roles of the lncRNA transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 1 (TPTE2P1), previously implicated in gallbladder cancer cell migration and invasion, were evaluated in CRC.
|
30382596 |
2019 |
|
Stage IV Gallbladder Cancer AJCC v8
|
0.020 |
Biomarker
|
disease |
BEFREE |
In this study, the roles of the lncRNA transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 1 (TPTE2P1), previously implicated in gallbladder cancer cell migration and invasion, were evaluated in CRC.
|
30382596 |
2019 |
|
Malignant neoplasm of gallbladder
|
0.020 |
Biomarker
|
disease |
BEFREE |
Our findings revealed the functional role of TPTE2P1 in human gallbladder cancer and suggested that TPTE2P1 could serve as a promising therapeutic target and a palliation option in human gallbladder cancer.
|
25676706 |
2015 |
|
Gallbladder Carcinoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Our findings revealed the functional role of TPTE2P1 in human gallbladder cancer and suggested that TPTE2P1 could serve as a promising therapeutic target and a palliation option in human gallbladder cancer.
|
25676706 |
2015 |
|
Stage 0 Gallbladder Cancer AJCC v8
|
0.020 |
Biomarker
|
disease |
BEFREE |
Our findings revealed the functional role of TPTE2P1 in human gallbladder cancer and suggested that TPTE2P1 could serve as a promising therapeutic target and a palliation option in human gallbladder cancer.
|
25676706 |
2015 |
|
Stage IIA Gallbladder Cancer AJCC v8
|
0.020 |
Biomarker
|
disease |
BEFREE |
Our findings revealed the functional role of TPTE2P1 in human gallbladder cancer and suggested that TPTE2P1 could serve as a promising therapeutic target and a palliation option in human gallbladder cancer.
|
25676706 |
2015 |
|
Stage IIB Gallbladder Cancer AJCC v8
|
0.020 |
Biomarker
|
disease |
BEFREE |
Our findings revealed the functional role of TPTE2P1 in human gallbladder cancer and suggested that TPTE2P1 could serve as a promising therapeutic target and a palliation option in human gallbladder cancer.
|
25676706 |
2015 |
|
Stage III Gallbladder Cancer AJCC v8
|
0.020 |
Biomarker
|
disease |
BEFREE |
Our findings revealed the functional role of TPTE2P1 in human gallbladder cancer and suggested that TPTE2P1 could serve as a promising therapeutic target and a palliation option in human gallbladder cancer.
|
25676706 |
2015 |
|
Stage IV Gallbladder Cancer AJCC v8
|
0.020 |
Biomarker
|
disease |
BEFREE |
Our findings revealed the functional role of TPTE2P1 in human gallbladder cancer and suggested that TPTE2P1 could serve as a promising therapeutic target and a palliation option in human gallbladder cancer.
|
25676706 |
2015 |
|
Malignant Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
TPTE2P1 knockdown also caused cancer cell apoptosis via the activation of the apoptosis regulator (BCL2)/caspase 3 signaling cascade.
|
30382596 |
2019 |
|
Colorectal Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
TPTE2P1 levels were significantly higher in CRC tissues than in adjacent normal tissues.
|
30382596 |
2019 |
|
Neoplasm Metastasis
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Our findings demonstrated that lncRNA-TPTE2P1 could serve as an early biomarker of metastasis and therapeutic target for HCC.
|
31114999 |
2019 |
|
Primary malignant neoplasm
|
0.010 |
Biomarker
|
group |
BEFREE |
TPTE2P1 knockdown also caused cancer cell apoptosis via the activation of the apoptosis regulator (BCL2)/caspase 3 signaling cascade.
|
30382596 |
2019 |
|
Liver carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Quantitative real-time polymerase chain reaction (qRT-PCR) was used to evaluate the expression level of lncRNA-TPTE2P1 in both HCC tissues and cell lines.
|
31114999 |
2019 |