SI, sucrase-isomaltase, 6476

N. diseases: 117; N. variants: 15
Disease: Intestinal metaplasia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0334037
Disease: Intestinal metaplasia
Intestinal metaplasia 		0.020 Biomarker phenotype BEFREE The expression of CDX2 precedes those of CDX1, sucrase-isomaltase, other intestine-specific genes (human defensin-5, alkaline phosphatase), and MUC2 during the progression of intestinal metaplasia. 11871772 2002
CUI: C0334037
Disease: Intestinal metaplasia
Intestinal metaplasia 		0.020 AlteredExpression phenotype BEFREE Columnar cells of specialized Barrett's epithelium express SI and are, therefore, phenotypically similar to those in incomplete intestinal metaplasia of the stomach with respect to intestinal gene expression. 8359653 1993