|
Malignant neoplasm of urinary bladder
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
High expression of both cytoplasmic DDX31 and p53 proteins correlated with poor prognosis in patients with MIBC, and blocking the DDX31/NCL interaction resulted in downregulation of EGFR/Akt signaling, eliciting an <i>in vivo</i> antitumor effect against bladder cancer.
|
29440146 |
2018 |
|
Bladder Neoplasm
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
High expression of both cytoplasmic DDX31 and p53 proteins correlated with poor prognosis in patients with MIBC, and blocking the DDX31/NCL interaction resulted in downregulation of EGFR/Akt signaling, eliciting an <i>in vivo</i> antitumor effect against bladder cancer.
|
29440146 |
2018 |
|
Malignant Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
These findings reveal that DDX31 cooperates with mutp53 and EGFR to promote progression of MIBC, and inhibition of DDX31/NCL formation may lead to potential treatment strategies for advanced MIBC.<b>Significance:</b> DDX31 cooperates with mutp53 and EGFR to promote progression of muscle invasive bladder cancer.<i>Cancer Res; 78(9); 2233-47.©2018 AACR</i>.
|
29440146 |
2018 |
|
Carcinoma of bladder
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
High expression of both cytoplasmic DDX31 and p53 proteins correlated with poor prognosis in patients with MIBC, and blocking the DDX31/NCL interaction resulted in downregulation of EGFR/Akt signaling, eliciting an <i>in vivo</i> antitumor effect against bladder cancer.
|
29440146 |
2018 |
|
Primary malignant neoplasm
|
0.010 |
Biomarker
|
group |
BEFREE |
These findings reveal that DDX31 cooperates with mutp53 and EGFR to promote progression of MIBC, and inhibition of DDX31/NCL formation may lead to potential treatment strategies for advanced MIBC.<b>Significance:</b> DDX31 cooperates with mutp53 and EGFR to promote progression of muscle invasive bladder cancer.<i>Cancer Res; 78(9); 2233-47.©2018 AACR</i>.
|
29440146 |
2018 |
|
Carcinoma of urinary bladder, invasive
|
0.010 |
Biomarker
|
disease |
BEFREE |
These findings reveal that DDX31 cooperates with mutp53 and EGFR to promote progression of MIBC, and inhibition of DDX31/NCL formation may lead to potential treatment strategies for advanced MIBC.<b>Significance:</b> DDX31 cooperates with mutp53 and EGFR to promote progression of muscle invasive bladder cancer.<i></i>.
|
29440146 |
2018 |
|
Medulloblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
In this review, we discuss a number of RNA binding proteins, including Musashi1 (MSI1), DEAD (Asp-Glu-Ala-Asp) box helicase 3 X-linked (DDX3X), DDX31, and cell division cycle and apoptosis regulator 1 (CCAR1), which play potentially critical roles in the growth and/or maintenance of medulloblastoma.
|
24608801 |
2014 |
|
Childhood Medulloblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
In this review, we discuss a number of RNA binding proteins, including Musashi1 (MSI1), DEAD (Asp-Glu-Ala-Asp) box helicase 3 X-linked (DDX3X), DDX31, and cell division cycle and apoptosis regulator 1 (CCAR1), which play potentially critical roles in the growth and/or maintenance of medulloblastoma.
|
24608801 |
2014 |
|
Adult Medulloblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
In this review, we discuss a number of RNA binding proteins, including Musashi1 (MSI1), DEAD (Asp-Glu-Ala-Asp) box helicase 3 X-linked (DDX3X), DDX31, and cell division cycle and apoptosis regulator 1 (CCAR1), which play potentially critical roles in the growth and/or maintenance of medulloblastoma.
|
24608801 |
2014 |
|
Renal Cell Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Immunohistochemical overexpression of DDX31 was an independent prognostic factor for patients with RCC.
|
23019224 |
2012 |
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Immunohistochemical overexpression of DDX31 was an independent prognostic factor for patients with RCC.
|
23019224 |
2012 |
|
Carcinogenesis
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Taken together, our findings define a mechanism through which control of the DDX31-NPM1 complex is likely to play critical roles in renal carcinogenesis.
|
23019224 |
2012 |