P2RY12, purinergic receptor P2Y12, 64805

N. diseases: 153; N. variants: 19
Disease: Angina, Unstable ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002965
Disease: Angina, Unstable
Angina, Unstable 		0.020 GeneticVariation disease BEFREE Our analysis showed that PPI significantly reduced the incidence of gastrointestinal (GI) bleed [22 vs. 66, odds ratio (OR)=0.37, confidence interval (CI)=0.23-0.61, P≤0.0001, I=0%], GI ulcers and GI erosions (7 vs. 18, OR=0.39, CI=0.16-0.94, P=0.04, I=0%), and the incidence of post-PCI unstable angina in patients treated with PPI and P2Y12 agents (46 vs. 67, OR=0.67, CI=0.45-0.99, P=0.05, I=0%). 29596078 2018
CUI: C0002965
Disease: Angina, Unstable
Angina, Unstable 		0.020 Biomarker disease BEFREE Differences in P2Y12 inhibitor administration were recorded on the basis of history of diabetes, age, and clinical presentation (unstable angina/non-STEMI vs. non-STEMI). 29309286 2018