P2RY12, purinergic receptor P2Y12, 64805

N. diseases: 153; N. variants: 19
Disease: Pain ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030193
Disease: Pain
Pain 		0.030 GeneticVariation phenotype BEFREE These effects on pain behaviors were replicated in P2Y12 knockout mice. 30778044 2019
CUI: C0030193
Disease: Pain
Pain 		0.030 GeneticVariation phenotype BEFREE We genotyped 31 single nucleotide polymorphisms (SNPs) throughout the P2RY12 gene and compared genotypes against pain measurements and opioid requirements in Japanese cancer pain patients (N = 90). 28472364 2018
CUI: C0030193
Disease: Pain
Pain 		0.030 Biomarker phenotype BEFREE Among the six P2Y12R antagonists evaluated in the pain studies, the selective P2Y12 receptor antagonist PSB-0739 was most potent upon intrathecal application. 24971933 2014