Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
ANOPHTHALMIA AND PULMONARY HYPOPLASIA
0.020 Biomarker disease BEFREE Mechanistic investigation of RAGE downstream in fibroblasts revealed a novel contribution of a mitogen-activated protein kinase kinase kinase (MAPKKK), tumor progression locus 2 (TPL2), which is required for positive regulation of PDAC cell motility through induction of cyclooxygenase 2 (COX2) and its catalyzed production of prostaglandin E2 (PGE2), a strong chemoattractive fatty acid. 31046874 2019
ANOPHTHALMIA AND PULMONARY HYPOPLASIA
0.020 AlteredExpression disease BEFREE WNK2 mRNA and protein expressions were lower in PDAC and CP compared with normal tissues both in patients and mouse models. 23912455 2014