SLC6A1, solute carrier family 6 member 1, 6529

N. diseases: 106; N. variants: 22
Disease: Anxiety Disorders ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders 		0.020 Biomarker group BEFREE To confirm that GAT1 can be also a molecular target for drugs used to treat other neurological and psychiatric diseases (e.g., pain and anxiety), in the in vivo part of this study, potential antinociceptive and anxiolytic-like properties of tiagabine, a selective GAT1 inhibitor, are described. 30222312 2019
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders 		0.020 Biomarker group BEFREE These data indicate a high load of genetic variance within SLC6A1 on pathological anxiety and highlight GAT-1 as a promising target for treatment of anxiety disorders with panic symptoms. 18607529 2009