CXADRP1, CXADR pseudogene 1, 653108

N. diseases: 272; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0028754
Disease: Obesity
Obesity
0.050 Biomarker disease BEFREE Therefore, PXR and CAR may become new therapeutic targets for metabolic syndrome, including obesity and diabetes. 30227815 2019
CUI: C0028754
Disease: Obesity
Obesity
0.050 Biomarker disease BEFREE The Role of PPAR and Its Cross-Talk with CAR and LXR in Obesity and Atherosclerosis. 29690611 2018
CUI: C0028754
Disease: Obesity
Obesity
0.050 Biomarker disease BEFREE A relevant number of studies using animal models of obesity suggest that CAR activation could be beneficial on the metabolic balance. 27180240 2016
CUI: C0028754
Disease: Obesity
Obesity
0.050 Biomarker disease BEFREE Given the metabolic benefits of CAR activation, CAR may represent an attractive therapeutic target to manage obesity and type 2 diabetes. 23330547 2013
CUI: C0028754
Disease: Obesity
Obesity
0.050 Biomarker disease BEFREE Given the recent finding that mice lacking CAR exhibit a profound decrease in resistance to weight loss during extended periods of caloric restriction, our findings have important implications in the development of drugs for the treatment of obesity and related diseases. 16825189 2006