BMP7, bone morphogenetic protein 7, 655

N. diseases: 197; N. variants: 3
Disease: Congenital defects ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0220810
Disease: Congenital defects
Congenital defects 		0.010 GeneticVariation group BEFREE Thus, BMP7 functions predominantly as a heterodimer with BMP2 or BMP4 during mammalian development, which may explain why mutations in either <i>Bmp4</i> or <i>Bmp7</i> lead to a similar spectrum of congenital defects in humans. 31566563 2019